A work spouse is a co-worker (usually of the opposite sex)^[1] with whom one shares a special relationship, having bonds similar to those of a marriage; such as, special confidences, loyalties, shared jokes and experiences, and an unusual degree of honesty or openness. The work spouse is a potentially key relationship when one’s actual spouse or boy/girlfriend is not able to understand the nuances of the workplace. While it is not unusual for the relationship to contain elements of flirtation, this relationship can be threatened rather than enhanced if it becomes sexual.